Florida Keys – TOP 10 Best-Rated Resorts & Hotels along the Overseas Highway

Florida Keys - TOP 10 Best-Rated Resorts & Hotels along the Overseas Highway

The Florida Keys, a string of idyllic islands stretching along the Overseas Highway, epitomize the essence of tropical bliss. With their turquoise waters, swaying palms, and vibrant culture, this slice of paradise beckons travelers from far and wide. Amidst this captivating landscape lie a plethora of resorts and hotels, each vying for attention with promises of unparalleled luxury and unforgettable experiences.

In this blog post, I embark on a journey to uncover the top 10 best-rated Resorts and Hotels along the Overseas Highway, offering a glimpse into the opulent amenities, stunning vistas, and exceptional hospitality that define the hospitality scene in the Keys. Whether you’re seeking relaxation, adventure, or a bit of both, join us as we traverse the sun-drenched shores and unveil the hidden gems that make the Florida Keys a destination like no other.

Whether you’re a seasoned traveler or a first-time visitor, prepare to be transported to a realm of unparalleled hospitality and natural splendor as we explore the premier lodging destinations of the Florida Keys.

1. Gilbert’s Resort

ADDRESS: 107900 Overseas Hwy, Key Largo, FL 33037

Gilbert's Resort - best resorts along the Overseas Highway and Florida Keys

Situated a mere 5.1 miles from the renowned John Pennekamp Coral Reef State Park and just 6 miles from the Key Largo Art Gallery, Gilbert’s Resort enjoys a prime location, making it an ideal base for exploring the wonders of the Florida Keys.

The resort boasts functional motel-style rooms that exude comfort and simplicity. Each room is thoughtfully appointed with modern amenities, including cable TV, minifridges, and private patios offering sweeping vistas of the shimmering ocean. For those desiring extra space and convenience, suites are available, complete with microwaves and pull-out sofas to accommodate larger groups or families.

Gilbert’s Resort goes beyond providing comfortable accommodations; it offers a plethora of amenities designed to enhance the guest experience. Step onto the private beach, where soft sands and azure waters beckon for leisurely strolls or basking in the warm Florida sun. Alternatively, take a refreshing dip in the outdoor pool, surrounded by lush tropical foliage, offering a welcome respite from the tropical heat.

For boating enthusiasts, Gilbert’s Resort boasts a full-service marina, catering to both seasoned sailors and novice adventurers alike. Whether you’re embarking on a fishing excursion or simply cruising along the crystalline waters, the marina provides everything you need for a memorable maritime experience.

After a day of exploration and relaxation, indulge in the vibrant nightlife scene at Gilbert’s Resort. Sip on refreshing cocktails at one of the two lively bars, including a charming tiki bar that hosts live entertainment, infusing the evenings with the infectious rhythms of the tropics.

2. Reefhouse Resort & Marina

ADDRESS: 103800 Overseas Hwy Mm 103.8, Key Largo, FL 33037

Reefhouse Resort & Marina - Top rated hotels and resorts in the Florida (Overseas Highway)

Reefhouse Resort & Marina is a picturesque oasis nestled along the pristine coastline, offering a harmonious blend of luxury accommodation, unparalleled natural beauty, and world-class amenities. Located on a secluded stretch of shoreline, the resort exudes an aura of tranquility and relaxation, making it the perfect escape for discerning travelers seeking a rejuvenating retreat.

The resort’s architecture seamlessly integrates with the surrounding environment, featuring traditional island-inspired designs infused with modern comforts. Guests are greeted by lush tropical gardens, swaying palm trees, and breathtaking views of the azure waters stretching out to the horizon.

Accommodation options at Reefhouse Resort & Marina are designed to cater to every preference and desire, ranging from spacious oceanfront villas to cozy beachfront cottages. Each room is meticulously appointed with elegant furnishings, plush bedding, and private balconies or terraces overlooking the mesmerizing seascape.

Reefhouse Resort & Marina stands as one of the premier destinations along the Overseas Highway and Florida Keys, celebrated for its unparalleled combination of luxury, natural beauty, and world-class amenities. Its idyllic location along this iconic route offers guests unparalleled access to the stunning scenery and vibrant culture of the Florida Keys archipelago.

3. Islander Resort

ADDRESS: 82100 Overseas Hwy, Islamorada, FL 33036

Islander Resort - Overseas Highway in the heart of the Florida Keys best rated hotels and resorts

Nestled along the stunning Overseas Highway in the heart of the Florida Keys, Islander Resort stands as a beacon of luxury and tranquility amidst the paradise of Islamorada. Renowned as one of the finest resorts in the region, Islander Resort offers discerning travelers a harmonious blend of opulence and simplicity, promising an unforgettable retreat.

At the heart of the Islander Resort experience lies its well-appointed rooms and suites, each meticulously designed to seamlessly blend indoor and outdoor living. Step into your private bungalow and feel the stresses of the outside world melt away as you’re enveloped by the serenity of lush tropical foliage and the gentle rustle of palm trees swaying in the ocean breeze.

The accommodations at Islander Resort are not merely places to rest your head but sanctuaries of comfort and elegance. From the crisp, white linens adorning plush beds to the sleek furnishings that exude modern sophistication, every detail has been carefully curated to ensure a stay that exceeds even the loftiest of expectations.

But it’s not just the interiors that captivate guests; it’s the seamless transition from indoor to outdoor living that truly sets Islander Resort apart. Step outside onto your private terrace or balcony and bask in the warm Florida sun, or retreat into the shade of a swaying hammock and lose yourself in a good book.

4. Lime Tree Bay Resort

ADDRESS: Mile Marker 68, FL-5, Layton, FL 33001

Lime Tree Bay Resort - check best places to stay in on the Florida Keys and Overseas Highway.

Lime Tree Bay Resort is indeed one of the finest resorts nestled in the heart of the Florida Keys along the Overseas Highway. Situated amidst the serene beauty of the Florida coastline, this resort offers an unparalleled tropical getaway experience.

The first thing that captivates visitors upon arrival is the breathtaking oceanfront location. Lime Tree Bay Resort boasts pristine sandy beaches and crystal-clear turquoise waters, inviting guests to unwind and soak up the sun. The resort’s lush tropical landscaping further enhances the tranquil ambiance, creating a true oasis for relaxation and rejuvenation.

Accommodations at Lime Tree Bay Resort are luxurious yet cozy, ranging from spacious oceanfront suites to charming beachfront cottages. Each accommodation is tastefully decorated and equipped with modern amenities to ensure a comfortable stay. Whether you’re traveling solo, with a partner, or with family and friends, there’s a perfect lodging option to suit every preference.

One of the highlights of staying at Lime Tree Bay Resort is the abundance of recreational activities available. From snorkeling and diving in the vibrant coral reefs to kayaking along the picturesque coastline, guests can immerse themselves in the natural wonders of the Florida Keys. Fishing enthusiasts will also appreciate the resort’s proximity to some of the best fishing spots in the area, offering opportunities to reel in a variety of game fish.

5. Tranquility Bay Beachfront Resort

ADDRESS: 2600 Overseas Hwy, Marathon, FL 33050

Tranquility Bay Beachfront Resort - one of the most beautiful resorts along the Overseas Highway.

Tranquility Bay Beachfront Resort stands as a shimmering gem along the famed Overseas Highway, nestled within the picturesque landscapes of the Florida Keys. Renowned for its unparalleled blend of luxury, natural beauty, and tranquil ambiance, it effortlessly secures its place among the best resorts dotting this scenic route.

As you traverse the Overseas Highway, often hailed as one of the most scenic drives in the United States, Tranquility Bay emerges as a beacon of hospitality and serenity. Situated on Marathon Key, this resort captures the essence of tropical paradise with its lush palm-lined pathways, pristine beaches, and breathtaking views of the azure waters of the Gulf of Mexico.

Upon arrival, guests are greeted by the warm hospitality that the Florida Keys are renowned for. The resort’s elegant architecture, reminiscent of classic Caribbean estates, blends seamlessly with the surrounding natural beauty. Each detail of Tranquility Bay reflects a commitment to luxury and comfort, from the impeccably appointed guest rooms and suites to the attentive service provided by the dedicated staff.

As the sun sets over the horizon, guests can gather around fire pits on the beach, sipping cocktails and savoring the tranquil beauty of the twilight hours. With its idyllic setting and unparalleled amenities, Tranquility Bay Beachfront Resort epitomizes the epitome of luxury and relaxation along the scenic Overseas Highway and throughout the Florida Keys, making it a must-visit destination for travelers seeking an unforgettable escape.

6. Isla Bella Beach Resort

ADDRESS: 1 Knights Key Blvd, Marathon, FL 33050

Isla Bella Beach Resort - check one of the most comfort hotels and resorts in the Florida Keys

Isla Bella Beach Resort stands as a shining gem among the picturesque Florida Keys, offering an unparalleled blend of luxury, natural beauty, and relaxation. Situated on the stunning coastline of Marathon Key, Isla Bella captivates visitors with its pristine white sand beaches, turquoise waters, and lush tropical surroundings. It effortlessly embodies the essence of a quintessential Florida Keys getaway.

Upon arrival, guests are greeted by the resort’s elegant architecture, seamlessly integrated with the island’s natural landscape. Isla Bella’s accommodations range from spacious guest rooms to luxurious suites and private beachfront villas, each meticulously designed to provide comfort and serenity. Whether guests choose to unwind on their private balcony overlooking the ocean or indulge in the resort’s world-class amenities, every aspect of Isla Bella exudes sophistication and charm.

The resort’s culinary offerings are a culinary delight, with multiple dining options that showcase the freshest local ingredients and innovative flavors. From gourmet seafood dishes to tropical cocktails enjoyed by the poolside, Isla Bella promises a culinary journey that tantalizes the taste buds and satisfies the soul.

In conclusion, Isla Bella Beach Resort stands as one of the crown jewels of the Florida Keys and Overseas Highway, offering a luxurious retreat where natural beauty meets unparalleled hospitality. With its idyllic setting, world-class amenities, and commitment to excellence, Isla Bella embodies the essence of a true tropical paradise and rightfully earns its place among the best resorts in the Florida Keys.

7. Little Palm Island Resort & Spa

ADDRESS: 28500 Overseas Hwy, Little Torch Key, FL 33042

Little Palm Island Resort & Spa - top 10 resorts and spa along the Overseas Highway.

Nestled amidst the turquoise waters of the Florida Keys, the Little Palm Island Resort & Spa stands as a beacon of luxury and tranquility. Tucked away on its own private island, accessible only by seaplane or boat, this exclusive retreat offers an unparalleled escape from the bustle of everyday life. With its pristine beaches, lush tropical gardens, and world-class amenities, it’s no wonder that the resort has become a must-stop destination for travelers along the Overseas Highway and Florida Keys.

From the moment guests arrive, they are enveloped in an atmosphere of serenity and sophistication. The resort’s intimate setting, with just 30 thatched-roof bungalows scattered throughout the island, ensures privacy and seclusion for all who visit. Each bungalow is elegantly appointed with luxurious furnishings, plush bedding, and modern amenities, providing the perfect blend of comfort and style.

One of the highlights of a stay at Little Palm Island is the exceptional dining experience offered at The Dining Room. Set against a backdrop of sweeping ocean views, this award-winning restaurant serves up a delectable array of gourmet dishes inspired by the flavors of the Caribbean and beyond. From freshly caught seafood to locally sourced produce, every meal is a culinary masterpiece to be savored.

For those seeking relaxation and rejuvenation, the resort’s SpaTerre offers a range of indulgent treatments designed to soothe the mind, body, and soul. Whether guests opt for a traditional massage, a rejuvenating facial, or a therapeutic body scrub, they are sure to leave feeling refreshed and revitalized. This is one of the best Florida Keys and Overseas Highway Resort!

8. Oceans Edge Resort & Marina Key West

ADDRESS: 5950 Peninsular Ave, Key West, FL 33040

Oceans Edge Resort & Marina Key West - where to stay during your Overseas Highway adventure. Best Overseas Highway places.

Oceans Edge Resort & Marina is a captivating oasis that beckons travelers along the Overseas Highway with its stunning waterfront location and luxurious amenities. As a must-see destination on the Florida Keys, Oceans Edge Resort & Marina offers a distinctive blend of upscale accommodations, world-class dining, and unparalleled recreational opportunities.

Boasting spacious rooms and suites with modern coastal decor, each offering breathtaking views of either the ocean or the resort’s marina, Oceans Edge provides a serene and stylish retreat for guests. Whether relaxing on a private balcony, sinking into plush bedding, or unwinding in a luxurious soaking tub, visitors are enveloped in comfort and tranquility from the moment they arrive.

The resort’s culinary offerings are equally impressive, with multiple dining options to satisfy every palate. From fresh seafood and tropical cocktails at the waterfront Yellowfin Bar & Grill to gourmet fare and fine wines at the upscale Ocean’s Edge Restaurant, guests can indulge in a culinary journey that celebrates the flavors of the Keys.

For those seeking adventure and exploration, Oceans Edge Resort & Marina offers an array of recreational activities both on land and at sea. Guests can take advantage of the resort’s private marina to embark on fishing charters, sunset cruises, or snorkeling excursions, or they can explore the nearby attractions of Key West, including Duval Street, Mallory Square, and the Ernest Hemingway Home and Museum.

9. Ocean Key Resort & Spa

ADDRESS: 0 Duval St, Key West, FL 33040

Ocean Key Resort & Spa - top 10 resorts & hotels in the Florida Keys.

Ocean Key Resort & Spa stands as a jewel along the Overseas Highway, nestled within the enchanting landscape of the Florida Keys. Renowned for its unparalleled luxury and impeccable service, this resort exemplifies the epitome of indulgence and relaxation.

Situated amidst the azure waters of the Gulf of Mexico, Ocean Key Resort & Spa offers breathtaking panoramic views that serve as a backdrop to an unforgettable getaway. Whether it’s lounging in a hammock overlooking the sparkling ocean or savoring a gourmet meal at the award-winning waterfront restaurant, every moment at this resort is infused with tranquility and sophistication.

The resort’s spa is a sanctuary of rejuvenation, where guests can immerse themselves in a world of blissful pampering and wellness. From invigorating massages to revitalizing skincare treatments, the spa offers a comprehensive menu of services designed to nourish the body, mind, and soul.

In addition to its world-class amenities, Ocean Key Resort & Spa boasts an array of recreational activities to suit every taste. Whether it’s snorkeling amidst vibrant coral reefs, exploring nearby historic landmarks, or simply lounging by the infinity pool with a refreshing cocktail in hand, guests are spoiled for choice when it comes to creating unforgettable memories. With its unparalleled beauty, luxurious accommodations, and unparalleled service, Ocean Key Resort & Spa stands as a beacon of excellence along the Overseas Highway and the Florida Keys, inviting travelers to experience the ultimate in tropical indulgence.

10. Opal Key Resort & Marina

ADDRESS: 245 Front St, Key West, FL 33040

Opal Key Resort & Marina - best Key West resorts and hotels

Opal Key Resort & Marina is a luxurious resort located in Key West, Florida. Known for its stunning waterfront views and upscale amenities, the resort offers a variety of accommodations, including spacious rooms and suites overlooking the Gulf of Mexico or the historic Key West Harbor.

The resort’s marina provides convenient access to boating and water activities, with options for chartering boats, fishing excursions, and sunset cruises. Guests can also relax by the infinity-edge pool, unwind at the spa, or dine at one of the on-site restaurants offering fresh seafood and tropical-inspired cuisine.

As travelers venture along the iconic Overseas Highway, Opal Key Resort & Marina emerges as a beacon of sophistication, beckoning visitors to indulge in an unforgettable escape. Boasting an exquisite waterfront location, the resort commands stunning vistas of the azure Gulf of Mexico and the historic Key West Harbor, captivating guests with panoramic views that redefine the notion of coastal splendor.

The allure of Opal Key Resort & Marina lies not only in its picturesque setting but also in its impeccable amenities and accommodations. Each room and suite is meticulously designed to embody refined elegance and comfort, providing a sanctuary where guests can unwind in style. From luxurious linens to modern furnishings, every detail is thoughtfully curated to ensure an unparalleled level of luxury.

I hope you enjoy my top 10 list of the best hotels and resorts along the scenic Overseas Highway in the Florida Keys. Have a great trip! Don’t forget to explore the best places to visit along the Florida Keys and Overseas Highway in my other post here: Overseas Highway – The 10 BEST STOPS Along the Florida Keys – Must-see places!

πŸ‘ Find out more:

Overseas Highway Florida Keys Travel Guide - 101 best stops by Mark Watson

Explore the finest attractions along the Overseas Highway and Florida Keys with my travel guide, ‘Florida Keys Overseas Highway Travel Guide – 101 Best Stops,’ now available on Amazon. This comprehensive guide is your ultimate companion for those seeking adventure and wonder along THE OVERSEAS HIGHWAY & FLORIDA KEYS! Discover 101 amazing places with convenient ‘Scan QR and go’ functionality for easy navigation.


Pacific Coast - Mark Watson

Mark Watson is a California-based member of a Los Angeles motorcycle club and an avid traveler. He has completed seven full journeys along the iconic Pacific Coast Highway on his Harley-Davidson and is passionate about promoting this historic drive to others. Mark has also explored the Alaska Highway and Route 66, and has authored four bestselling travel guides on Amazon: “Route 66 Travel Guide – 202 Amazing Places,” “Alaska Highway Travel Guide – 202 Best Stops,”, “Pacific Coast Highway Travel Guide – 202 Best Stops”, and “Florida Keys Overseas Highway Travel Guide – 101 Best Stops.”

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